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Article

Folic acid supplementation during pregnancy may protect against depression 21 months after pregnancy, an effect modified by MTHFR C677T genotype.

European journal of clinical nutrition - 1 Jan 2012

Lewis S J, Araya R, Leary S, Smith G Davey, Ness A

Abstract excerpt

BACKGROUND/OBJECTIVES: As low folate status has been implicated in depression, high folate intake, in the form of supplements, during pregnancy might offer protection against depression during pregnancy and postpartum. SUBJECTS/METHODS: We examined the association between change in self-reported depressive symptoms (Edinburgh Postnatal Depression Scale) at different timepoints during and following pregnancy and...

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Source

Identifiers

PMID: 21772318
DOI: 10.1038/ejcn.2011.136

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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