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Tau and DNA Damage in Neurodegeneration

7 Dec 2020

Abstract excerpt

Neurodegenerative disorders are a family of incurable conditions. Among them, Alzheimer’s disease and tauopathies are the most common. Pathological features of these two disorders are synaptic loss, neuronal cell death and increased DNA damage. A key pathological protein for the onset and progression of the conditions is the protein tau, a microtubule-binding protein highly expressed in neurons and encoded by the...

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PMID: 33297375
DOI: 10.3390/brainsci10120946

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