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Article

CCDC170 affects breast cancer apoptosis through IRE1 pathway.

Aging - 3 Dec 2020

Wang Qiong, Zhao Yanrui, Zheng Hong, Wang Qinghua, Wang Wei, Liu Ben, Han Hongwei, Zhang Lina, Chen Kexin

Abstract excerpt

Genome-wide association studies have revealed that multiple single-nucleotide polymorphisms in the intergenic region between estrogen receptor 1 and coiled-coil domain containing 170 (CCDC170) are associated with breast cancer risk. We performed microarray and bioinformatics analyses to identify genes that were induced upon CCDC170 overexpression, and confirmed our findings by evaluating paraffin-embedded breast...

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Identifiers

PMID: 33291081
DOI: 10.18632/aging.202315
PMCID: PMC7835043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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