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Article

The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network.

EBioMedicine - 1 Aug 2017

Jiang Pengtao, Li Yueran, Poleshko Andrey, Medvedeva Valentina, Baulina Natalia, Zhang Yongchao, Zhou Yan, Slater Carolyn M, Pellegrin Trinity, Wasserman Jason, Lindy Michael, Efimov Andrey, Daly Mary, Katz Richard A, Chen Xiaowei

Abstract excerpt

Genome-Wide Association Studies (GWAS) and subsequent fine-mapping studies (>50) have implicated single nucleotide polymorphisms (SNPs) located at the CCDC170/C6ORF97-ESR1 locus (6q25.1) as being associated with the risk of breast cancer. Surprisingly, our analysis using genome-wide differential allele-specific expression (DASE), an indicator for breast cancer susceptibility, suggested that the genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28687497
DOI: 10.1016/j.ebiom.2017.06.024
PMCID: PMC5552109

Genes

ESR1
ATAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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