Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ERBB2 Pathway in Biliary Tract Carcinoma: Clinical Implications of a Targetable Pathway.

Oncology research and treatment - 1 Jan 2021

Jacobi Oded, Ross Jeffrey S, Goshen-Lago Tal, Haddad Riad, Moore Assaf, Sulkes Aaron, Brenner Baruch, Ben-Aharon Irit

Abstract excerpt

BACKGROUND/AIMS: Current chemotherapy regimens for cholangiocarcinoma (CCA) yield poor outcomes, with a median overall survival of <12 months. Recent data on the genomic landscape of CCAs have created opportunities for targeted therapy. Yet, data regarding its efficacy are scarce. We aimed to describe the genomic landscape of a CCA patient cohort using next-generation sequencing (NGS), focusing on the ERBB/EFGR...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Receptor, ErbB-2
Share to Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bile Duct Neoplasms

Share to Bile Ducts, Intrahepatic

Share to Cholangiocarcinoma

Share to Gastrointestinal Neoplasms

Share to Mutation

Share to Trastuzumab

Source

Identifiers

PMID: 33279901
DOI: 10.1159/000511919

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ERBB2 Pathway in Biliary Tract Carcinoma: Clinical Implications of a Targetable Pathway.PMID 33279901Read ↗

Characterization of EGFR family gene aberrations in cholangiocarcinomaSemantic proximity Read ↗

Biliary cancer: Utility of next-generation sequencing for clinical management.Semantic proximity Read ↗

Genomic spectra of biliary tract cancer.Semantic proximity Read ↗

Molecular profiling of biliary cancers reveals distinct molecular alterations and potential therapeutic targetsSemantic proximity Read ↗

Targeted Therapies in Advanced Biliary Tract Cancer: An Evolving ParadigmSemantic proximity Read ↗

Molecular Testing for Intrahepatic Cholangiocarcinoma: What, When, How?Semantic proximity Read ↗

The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets.Semantic proximity Read ↗

Genomic feature and potential therapeutic target for cholangiocarcinomaSemantic proximity Read ↗

HER2 gene (ERBB2) amplification is a rare event in non-liver-fluke associated cholangiocarcinogenesisSemantic proximity Read ↗

New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next-Generation SequencingSemantic proximity Read ↗

Targeted therapies in advanced biliary malignancies: a clinical review.Semantic proximity Read ↗

Translating cancer genomics for precision oncology in biliary tract cancers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.