Article
Conditioned medium harvested from Hif1α engineered mesenchymal stem cells ameliorates LAD-occlusion -induced injury in rat acute myocardial ischemia model.
The international journal of biochemistry & cell biology - 1 Jan 2021
Alijani-Ghazyani Zahra, Roushandeh Amaneh Mohammadi, Sabzevari Reza, Salari Arsalan, Razavi Toosi Mohammad Taghi, Jahanian-Najafabadi Ali, Roudkenar Mehryar Habibi
Abstract excerpt
Acute myocardial infarction (AMI) is the most common type of ischemic heart diseases with a high mortality rate. Although recent advances in medical cares and therapies have increased the patient's outcomes, but, still there is no real and effective therapeutic modality for AMI. Hence, development of novel therapeutic strategies is under focus of investigations. MSCs-based therapy has been proposed for AMI,...
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