Article
Intramyocardial injection of hypoxia-preconditioned adipose-derived stromal cells treats acute myocardial infarction: an in vivo study in swine.
Cell and tissue research - 1 Nov 2014
Jiang Yiyao, Chang Pengyu, Pei Yu, Li Baojiang, Liu Yongjun, Zhang Zhang, Yu Jing, Zhu Delin, Liu Xiaocheng
Abstract excerpt
Hypoxic preconditioning is a promising method for improving the anti-apoptotic and paracrine signaling capabilities of adipose-derived stromal cells (ADSCs). The purpose of this study was to analyze the influence of different hypoxic conditions on ADSCs and the therapeutic effects of hypoxia-preconditioned ADSCs (HPADSCs) on an animal model of myocardial infarction (MI). For the in vitro studies, ADSCs were...
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