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Article

Chemokine mediated signalling within arteries promotes vascular smooth muscle cell recruitment.

Communications biology - 4 Dec 2020

Stratman Amber N, Burns Margaret C, Farrelly Olivia M, Davis Andrew E, Li Wenling, Pham Van N, Castranova Daniel, Yano Joseph J, Goddard Lauren M, Nguyen Oliver, Galanternik Marina Venero, Bolan Timothy J, Kahn Mark L, Mukouyama Yoh-Suke, Weinstein Brant M

Abstract excerpt

The preferential accumulation of vascular smooth muscle cells (vSMCs) on arteries versus veins during early development is a well-described phenomenon, but the molecular pathways underlying this polarization are not well understood. In zebrafish, the cxcr4a receptor (mammalian CXCR4) and its ligand cxcl12b (mammalian CXCL12) are both preferentially expressed on arteries at time points consistent with the arrival...

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Source

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Identifiers

PMID: 33277595
DOI: 10.1038/s42003-020-01462-7
PMCID: PMC7719186

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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