NGS-based typings for 7 HLA loci in three populations from Rio de Janeiro, RJ, Brazil.

doi:10.1016/j.humimm.2020.11.003

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Article

NGS-based typings for 7 HLA loci in three populations from Rio de Janeiro, RJ, Brazil.

Human immunology - 1 Jan 2021

Vianna Romulo, Hanhoerderster Leonardo, Cardoso Juliana, Cristóvão Porto Luís

Abstract excerpt

We investigated HLA class I (HLA-A, -B, and -C) and class II (HLA-DRB1, -DQB1, -DPA1, and -DPB1) alleles by NGS-based typing among 759 Brazilian individuals from three populations in the Rio de Janeiro city based on their self-declared skin color (Caucasian, N = 521, AFND-ID: 3730; Parda, N = 170, AFND-ID: 3728; Black, N = 68, AFND-ID: 3727) to calculate allelic and haplotypic frequencies, plus linkage...

Topics

Alleles
Brazil
Gene Frequency
Genetics, Population
Haplotypes
High-Throughput Nucleotide Sequencing
Histocompatibility Antigens Class I
Histocompatibility Antigens Class II
Humans
Linkage Disequilibrium
Population Groups

Source

Open in PubMed

Identifiers

PMID: 33267971
DOI: 10.1016/j.humimm.2020.11.003

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