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Article

A CNTNAP1 Missense Variant Is Associated with Canine Laryngeal Paralysis and Polyneuropathy.

Genes - 27 Nov 2020

Letko Anna, Minor Katie M, Friedenberg Steven G, Shelton G Diane, Salvador Jill Pesayco, Mandigers Paul J J, Leegwater Peter A J, Winkler Paige A, Petersen-Jones Simon M, Stanley Bryden J, Ekenstedt Kari J, Johnson Gary S, Hansen Liz, Jagannathan Vidhya, Mickelson James R, Drögemüller Cord

Abstract excerpt

Laryngeal paralysis associated with a generalized polyneuropathy (LPPN) most commonly exists in geriatric dogs from a variety of large and giant breeds. The purpose of this study was to discover the underlying genetic and molecular mechanisms in a younger-onset form of this neurodegenerative disease seen in two closely related giant dog breeds, the Leonberger and Saint Bernard. Neuropathology of an affected dog...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33261176
DOI: 10.3390/genes11121426
PMCID: PMC7761076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A CNTNAP1 Missense Variant Is Associated with Canine Laryngeal Paralysis and Polyneuropathy.PMID 33261176Read ↗

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