Article
Comparative Genomics of Atypical Enteropathogenic Escherichia coli from Kittens and Children Identifies Bacterial Factors Associated with Virulence in Kittens.
Infection and immunity - 16 Feb 2021
Watson Victoria E, Hazen Tracy H, Rasko David A, Jacob Megan E, Elfenbein Johanna R, Stauffer Stephen H, Gookin Jody L
Abstract excerpt
Typical enteropathogenic Escherichia coli (tEPEC) is a leading cause of diarrhea and associated death in children worldwide. Atypical EPEC (aEPEC) lacks the plasmid encoding bundle-forming pili and is considered less virulent, but the molecular mechanism of virulence is poorly understood. We recently identified kittens as a host for aEPEC where intestinal epithelial colonization was associated with diarrheal...
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