Evolution of atypical enteropathogenic E. coli by repeated acquisition of LEE pathogenicity island variants.

doi:10.1038/nmicrobiol.2015.10

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Article

Evolution of atypical enteropathogenic E. coli by repeated acquisition of LEE pathogenicity island variants.

Nature microbiology - 18 Jan 2016

Ingle Danielle J, Tauschek Marija, Edwards David J, Hocking Dianna M, Pickard Derek J, Azzopardi Kristy I, Amarasena Thakshila, Bennett-Wood Vicki, Pearson Jaclyn S, Tamboura Boubou, Antonio Martin, Ochieng John B, Oundo Joseph, Mandomando Inácio, Qureshi Shahida, Ramamurthy Thandavarayan, Hossain Anowar, Kotloff Karen L, Nataro James P, Dougan Gordon, Levine Myron M, Robins-Browne Roy M, Holt Kathryn E

Abstract excerpt

Atypical enteropathogenic Escherichia coli (aEPEC) is an umbrella term given to E. coli that possess a type III secretion system encoded in the locus of enterocyte effacement (LEE), but lack the virulence factors (stx, bfpA) that characterize enterohaemorrhagic E. coli and typical EPEC, respectively. The burden of disease caused by aEPEC has recently increased in industrialized and developing nations, yet the...

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PMID: 27571974
DOI: 10.1038/nmicrobiol.2015.10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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