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Article

KRAS mutations are negatively correlated with immunity in colon cancer.

Aging - 26 Nov 2020

Fu Xiaorui, Wang Xinyi, Duanmu Jinzhong, Li Taiyuan, Jiang Qunguang

Abstract excerpt

The heterogeneity of colon cancer tumors suggests that therapeutics targeting specific molecules may be effective in only a few patients. It is therefore necessary to explore gene mutations in colon cancer. In this study, we obtained colon cancer samples from The Cancer Genome Atlas, and the International Cancer Genome Consortium. We evaluated the landscape of somatic mutations in colon cancer and found that KRAS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33254149
DOI: 10.18632/aging.202182
PMCID: PMC7834984

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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