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Article

Genetic signatures for lineage/sublineage classification of HPV16, 18, 52 and 58 variants.

Virology - 15 Jan 2021

Ou Zhihua, Chen Zigui, Zhao Yanping, Lu Haorong, Liu Wei, Li Wangsheng, Ren Peidi, Geng Chunyu, Xiao Minfeng, Hu Guohai, Wu Di, Wang Xiaman, Liu Na, Zhu Shida, Lu Ling, Li Junhua

Abstract excerpt

Increasing evidences indicate that high-risk HPV variants are heterogeneous in carcinogenicity and ethnic dispersion. In this work, we identified genetic signatures for convenient determination of lineage/sublineage of HPV16, 18, 52 and 58 variants. Using publicly available genomes, we found that E2 of HPV16, L2 of HPV18, L1 and LCR of HPV52, and L2, LCR and E1 of HPV58 contain the proper genetic signature for...

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PMID: 33238224
DOI: 10.1016/j.virol.2020.11.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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