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Article

Normal Somatic Mutations in Cancer Transformation.

Cancer cell - 8 Feb 2021

Wijewardhane Neshika, Dressler Lisa, Ciccarelli Francesca D

Abstract excerpt

Gene alterations play a prominent role in driving cancer initiation and progression. However, the genetic events that occur in normal cells prior to tumorigenesis are still unknown. Recent studies have started to map somatic mutations in normal human tissues, and here we discuss their implications for our understanding of tumorigenesis.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33220180
DOI: 10.1016/j.ccell.2020.11.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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