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Article

Lipocalin 2 as a potential systemic biomarker for central serous chorioretinopathy

19 Nov 2020

Abstract excerpt

No systemic biomarker of Central Serous Chorioretinopathy (CSCR) has been identified. Lipocalin 2 (LCN2 or NGAL), alone or complexed with MMP-9 (NGAL/MMP-9), is increased in several retinal disorders. Serum levels of LCN2 and NGAL/MMP-9 were measured in CSCR patients (n = 147) with chronic (n = 76) or acute/recurrent disease (n = 71) and in age- and sex-matched healthy controls (n = 130). Samples with CRP > 5...

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PMID: 33214636
DOI: 10.1038/s41598-020-77202-y

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