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Article

Changes in Matrix Metalloproteinase Network in a Spontaneous Autoimmune Uveitis Model

13 Jan 2011

Abstract excerpt

PURPOSE: Autoimmune uveitis is a sight-threatening disease in which autoreactive T cells cross the blood-retinal barrier. Molecular mechanisms contributing to the loss of eye immune privilege in this autoimmune disease are not well understood. In this study, the authors investigated the changes in the matrix metalloproteinase network in spontaneous uveitis. METHODS: Matrix metalloproteinase (MMP) MMP2, MMP9, and...

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PMID: 21228380
DOI: 10.1167/iovs.10-6475

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