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Article

Decreased concentrations of intracellular signaling proteins in colon cancer patients with BRAF mutations.

Scientific reports - 18 Nov 2020

Olsen Dorte Aa, Thomsen Caroline E B, Andersen Rikke F, Madsen Jonna S, Jakobsen Anders, Brandslund Ivan

Abstract excerpt

The activation of intracellular signaling pathways plays a critical role in cancer pathogenesis. The current study aims to quantify intracellular signaling proteins in localized colon cancer tissue to investigate the prognostic value of these biomarkers and elucidate their possible relations to mutation status. Colon cancer tissue and autologous reference tissue were collected from 176 patients who underwent...

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Identifiers

PMID: 33208845
DOI: 10.1038/s41598-020-77109-8
PMCID: PMC7675974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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