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Article

The prognostic value of simultaneous tumor and serum RAS/RAF mutations in localized colon cancer.

Cancer medicine - 1 May 2017

Thomsen Caroline Emilie B, Appelt Ane Lindegaard, Andersen Rikke Fredslund, Lindebjerg Jan, Jensen Lars Henrik, Jakobsen Anders

Abstract excerpt

The impact of RAS/RAF mutations in localized colon cancer needs clarification. Based on analysis of tumor-specific DNA, this study aimed at elucidating the prognostic influence of mutational status in tumor and serum using an extended panel of mutations. The study retrospectively included 294 patients with curatively resected stage I-III adenocarcinoma of the colon. Mutations in tumor and serum were determined at...

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Source

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Identifiers

PMID: 28378527
DOI: 10.1002/cam4.1051
PMCID: PMC5430097

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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