Article
Primary Sjögren's Syndrome of Early and Late Onset: Distinct Clinical Phenotypes and Lymphoma Development.
Frontiers in immunology - 1 Jan 2020
Goules Andreas V, Argyropoulou Ourania D, Pezoulas Vasileios C, Chatzis Loukas, Critselis Elena, Gandolfo Saviana, Ferro Francesco, Binutti Marco, Donati Valentina, Zandonella Callegher Sara, Venetsanopoulou Aliki, Zampeli Evangelia, Mavrommati Maria, Voulgari Paraskevi V, Exarchos Themis, Mavragani Clio P, Baldini Chiara, Skopouli Fotini N, Fotiadis Dimitrios I, De Vita Salvatore, Moutsopoulos Haralampos M, Tzioufas Athanasios G
Abstract excerpt
Objectives: To study the clinical, serological and histologic features of primary Sjögren's syndrome (pSS) patients with early (young ≤35 years) or late (old ≥65 years) onset and to explore the differential effect on lymphoma development. Methods: From a multicentre study population of 1997 consecutive pSS patients, those with early or late disease onset, were matched and compared with pSS control patients of...
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