Childhood-onset versus adult-onset Sjögren Syndrome: Clinical phenotype, disease activity, and predictors of organ damage in a national multicenter cohort.

doi:10.1016/j.semarthrit.2026.153060

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Childhood-onset versus adult-onset Sjögren Syndrome: Clinical phenotype, disease activity, and predictors of organ damage in a national multicenter cohort.

Seminars in arthritis and rheumatism - 1 Oct 2026

Kilic Konte Elif, Sahin Sezgin, Firat Sentürk Esra, Yekedüz Bülbül Aydan, Arslanoglu Ceyda, Orhan Erkan Mehmet, Kücükali Batuhan, Ugur Es Yasemin, Kara Canlioglu Neslihan, Koker Oya, Kilbas Gülsah, Oguz Gorkem, Sahin Cansu, Selim Kul Mehmet, Miray Kisla Ekinci Rabia, Sümer Gokce, Anıl Akın Ozan, Ilgaz Tüzen Hande, Bozkaya Yücel Burcu, Kisaoglu Hakan, Emine Sonmez Hafize, Ozen Balci Merve, Isgüder Rana, Sener Seher, Demirkan Fatma Gül, Can Eroglu Ender, Kacmaz Hatice Melisa, Cakmak Figen, Haslak Fatih, Türkucar Serkan, Celikel Elif, Gezgin Yildirim Deniz, Demir Selcan, Sag Erdal, Basaran Ozge, Kasap Demir Belde, Kilic Sara S, Kalyoncu Mukaddes, Balat Ayse, Aktay Ayaz Nuray, Pac Kisaarslan Aysenur, Sozeri Betül, Yüksel Selcuk, Ugurlu Serdal, Kasapcopur Ozgur

Abstract excerpt

OBJECTIVES: To compare the clinical, immunological, and diagnostic characteristics of childhood-onset (coSS) versus adult-onset Sjögren syndrome (aoSS), assess disease activity and damage accrual, and identify independent predictors of organ damage. METHODS: This national, multicenter retrospective cohort included 197 patients, 115 (58.4%) with coSS and 82 (41.6%) with aoSS. Clinical, laboratory, and outcome data...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Humans

Female

Sjogren's Syndrome

Age of Onset

Retrospective Studies

Phenotype

Adult

Male

Severity of Illness Index

Middle Aged

Child

Source

Open in PubMed

Identifiers

PMID: 42659937
DOI: 10.1016/j.semarthrit.2026.153060

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Childhood-onset versus adult-onset Sjögren Syndrome: Clinical phenotype, disease activity, and predictors of organ damage in a national multicenter cohort.PMID 42659937Read ↗

Childhood-onset of primary Sjögren's syndrome: phenotypic characterization at diagnosis of 158 children.Semantic proximity Read ↗

Childhood-onset of primary Sjogren syndrome Phenotypic characterization at diagnosis of 158 childrenSemantic proximity Read ↗

Distinct clinical phenotypes of primary Sjögren's syndrome differ by onset age: a retrospective study of 742 cases and review of the literature.Semantic proximity Read ↗

Clinical phenotypes, classification, and long-term outcomes of childhood-onset Sjögren's disease into adulthood: a single-centre cohort study.Semantic proximity Read ↗

Epidemiological profile and north-south gradient driving baseline systemic involvement of primary Sjögren's syndrome.Semantic proximity Read ↗

Differences in clinical phenotypes of primary Sjögren's syndrome depending on early or late onset.Semantic proximity Read ↗

Brazilian Registry of Sjögren’s Disease (BRAS): a full picture of Sjögren’s diseaseSemantic proximity Read ↗

Sjögren's syndrome: one year in review 2023Semantic proximity Read ↗

Sjögren's syndrome: one year in review 2022Semantic proximity Read ↗

Severe, life-threatening phenotype of primary Sjögren's syndrome: clinical characterisation and outcomes in 1580 patients (GEAS-SS Registry).Semantic proximity Read ↗

Childhood Sjögren syndrome: insights from adults and animal models.Semantic proximity Read ↗

Recent advances in primary Sjogren's syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.