Article
Chicken Egg Yolk Antibodies (IgYs) block the binding of multiple SARS-CoV-2 spike protein variants to human ACE2.
International immunopharmacology - 1 Jan 2021
Wei Shuangshi, Duan Shengbao, Liu Xiaomei, Wang Hongmei, Ding Shaohua, Chen Yezhou, Xie Jinsong, Tian Jingjing, Yu Nong, Ge Pingju, Zhang Xinglin, Chen Xiaohong, Li Yong, Meng Qinglin
Abstract excerpt
The SARS-CoV-2 virus is still spreading worldwide, and there is an urgent need to effectively prevent and control this pandemic. This study evaluated the potential efficacy of Egg Yolk Antibodies (IgY) as a neutralizing agent against the SARS-CoV-2. We investigated the neutralizing effect of anti-spike-S1 IgYs on the SARS-CoV-2 pseudovirus, as well as its inhibitory effect on the binding of the coronavirus spike...
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