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Article

Cytologically targeted next-generation sequencing: a synergy for diagnosing urothelial carcinoma.

Journal of the American Society of Cytopathology - 1 Jan 2000

Harris Taylor, Sheel Ankur, Zong Yang, Hutchinson Lloyd M, Cornejo Kristine M, Bubendorf Lukas, Yates Jennifer, Fischer Andrew H

Abstract excerpt

INTRODUCTION: Cytology and cystoscopy are used to detect urothelial carcinoma (UC), but together they still fail to detect some UC cases and are not suitable for screening asymptomatic individuals. Mutations are present in more than 98% of UC, mutations have therapeutic significance, and they can be detected by next generation sequencing (NGS) in urine samples. We review the role of NGS in UC detection. MATERIALS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33184010
DOI: 10.1016/j.jasc.2020.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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