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Article

Transmission analysis of a large tuberculosis outbreak in London: a mathematical modelling study using genomic data.

Microbial genomics - 1 Nov 2020

Xu Yuanwei, Stockdale Jessica E, Naidu Vijay, Hatherell Hollie, Stimson James, Stagg Helen R, Abubakar Ibrahim, Colijn Caroline

Abstract excerpt

Outbreaks of tuberculosis (TB) - such as the large isoniazid-resistant outbreak centred on London, UK, which originated in 1995 - provide excellent opportunities to model transmission of this devastating disease. Transmission chains for TB are notoriously difficult to ascertain, but mathematical modelling approaches, combined with whole-genome sequencing data, have strong potential to contribute to transmission...

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Identifiers

PMID: 33174832
DOI: 10.1099/mgen.0.000450
PMCID: PMC7725332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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