Article
Single nucleotide polymorphisms in LCAT may contribute to dyslipidaemia in HIV-infected individuals on HAART in a Ghanaian population.
Scientific reports - 10 Nov 2020
Bani Simon Bannison, Danquah Kwabena Owusu, Obirikorang Christian, Owiredu William K B A, Quaye Lawrence, Muonir Der Edmund, Acheampong Emmanuel, Adams Yussif, Dapare Peter Paul M, Banyeh Moses, Anto Enoch Odame, Sakyi Samuel Asamoah
Abstract excerpt
Highly active antiretroviral therapy (HAART) is known to cause lipid abnormalities such as dyslipidaemia in HIV-infected individuals. Yet, dyslipidaemia may not independently occur as it may be worsened by single nucleotide polymorphisms (SNPs) in lecithin cholesterol acyltransferase (LCAT) and lipoprotein lipase (LPL). This case-control study was conducted in three-selected hospitals in the Northern part of...
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