Article
Characterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing.
Nature communications - 10 Nov 2020
Lang Guan-Tian, Jiang Yi-Zhou, Shi Jin-Xiu, Yang Fan, Li Xiao-Guang, Pei Yu-Chen, Zhang Chen-Hui, Ma Ding, Xiao Yi, Hu Peng-Chen, Wang Hai, Yang Yun-Song, Guo Lin-Wei, Lu Xun-Xi, Xue Meng-Zhu, Wang Peng, Cao A-Yong, Ling Hong, Wang Zhong-Hua, Yu Ke-Da, Di Gen-Hong, Li Da-Qiang, Wang Yun-Jin, Yu Ying, Shi Le-Ming, Hu Xin, Huang Wei, Shao Zhi-Ming
Abstract excerpt
The remarkable advances in next-generation sequencing technology have enabled the wide usage of sequencing as a clinical tool. To promote the advance of precision oncology for breast cancer in China, here we report a large-scale prospective clinical sequencing program using the Fudan-BC panel, and comprehensively analyze the clinical and genomic characteristics of Chinese breast cancer. The mutational landscape...
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