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Novel homozygous truncating variants in ZMYND15 causing severe oligozoospermia and their implications for male infertility

10 Nov 2020

Abstract excerpt

Sequence variants of ZMYND15 cause azoospermia in humans, but they have not yet been reported in infertile men with severe oligozoospermia (SO). We performed whole-exome and Sanger sequencing to identify suspected causative variants in 414 idiopathic participating infertile men with SO or azoospermia. Three novel homozygous truncating variants in ZMYND15 were identified in three of the 219 (1.37%) unrelated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33169450
DOI: 10.1002/humu.24138

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