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Article

Novel mutations in ZMYND15 are associated with male infertility with oligozoospermia/azoospermia.

Journal of assisted reproduction and genetics - 1 May 2025

Wei Chunjia, Lu Yingchi, Yi Sibing, Liang Yaoqiong, Meng Lanlan, Tan Chen, Du Juan, Lin Ge, Tan Yue-Qiu, Gan Xianyou, Tu Chaofeng, Qin Zailong

Abstract excerpt

PURPOSE: This study aimed to identify the genetic causes of male infertility associated with oligozoospermia/azoospermia in two unrelated Chinese families. METHODS: Whole-exome sequencing (WES) and Sanger sequencing were performed on peripheral blood samples from three infertile individuals with reduced sperm counts. Semen analysis data were collected, and sperm morphology was evaluated using hematoxylin and...

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Source

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Identifiers

PMID: 40240737
DOI: 10.1007/s10815-025-03480-y
PMCID: PMC12167407

Genes

ZMYND15

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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