Article
Machine Learned Cellular Phenotypes in Cardiomyopathy Predict Sudden Death.
Circulation research - 22 Jan 2021
Rogers Albert J, Selvalingam Anojan, Alhusseini Mahmood I, Krummen David E, Corrado Cesare, Abuzaid Firas, Baykaner Tina, Meyer Christian, Clopton Paul, Giles Wayne, Bailis Peter, Niederer Steven, Wang Paul J, Rappel Wouter-Jan, Zaharia Matei, Narayan Sanjiv M
Abstract excerpt
RATIONALE: Susceptibility to VT/VF (ventricular tachycardia/fibrillation) is difficult to predict in patients with ischemic cardiomyopathy either by clinical tools or by attempting to translate cellular mechanisms to the bedside. OBJECTIVE: To develop computational phenotypes of patients with ischemic cardiomyopathy, by training then interpreting machine learning of ventricular monophasic action potentials (MAPs)...
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