Article
Identification of Genetic Susceptibility Factors Associated with Canine Gastric Dilatation-Volvulus.
Genes - 5 Nov 2020
Piras Ignazio S, Perdigones Nieves, Zismann Victoria, Briones Natalia, Facista Salvatore, Rivera José Luis, Rozanski Elizabeth, London Cheryl A, Hendricks William P D
Abstract excerpt
Canine gastric dilatation-volvulus (GDV) is a common life-threatening condition occurring primarily in large and giant breeds with a 3.9% to 36.7% lifetime risk. The genetic correlates of GDV have not previously been systematically explored. We undertook an inter-breed genome-wide association analysis (GWAS) of 253 dogs from ten breeds including 106 healthy dogs and 147 dogs with at least one GDV episode. SNP...
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