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Characterization of canine epidermal organoid cultures by immunohistochemical analysis and quantitative PCR

9 Nov 2020

Abstract excerpt

BACKGROUND: Keratinocyte organoids can be used as a tool to evaluate epidermal structure, function and dysfunction. OBJECTIVES: To optimize the canine keratinocyte organoid system and produce organoids that are structurally equivalent to in vivo canine epidermis, in order to enable studies that focus on epidermal diseases and diseases resulting from an impaired epidermal barrier. ANIMALS: Skin biopsies were...

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PMID: 33165993
DOI: 10.1111/vde.12914

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