Article
Activities and polymorphisms of MMP-2 and MMP-9, smoking, diabetes and risk of prostate cancer.
Molecular biology reports - 1 Dec 2020
Kiani Amir, Kamankesh Marjan, Vaisi-Raygani Asad, Moradi Mahmoud-Reza, Tanhapour Maryam, Rahimi Zohreh, Elahi-Rad Saeed, Bahrehmand Fariborz, Aliyari Mahdieh, Aghaz Faranak, Mozafari Hadi, Rezvani Nayebali, Haghnazari Lida, Pourmotabbed Tayebeh
Abstract excerpt
Matrix metalloproteinases (MMPs) are a group of zinc dependent enzymes that are involved in tumor cell invasion and metastasis. The role of MMP-2 and -9 genetic polymorphism in different malignancies has been the subject of numerous studies. The present research has attempted to discover any positive correlation between MMP-2 and MMP-9 SNPs and prostate cancer (PCa) in patients with a history of either diabetes...
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