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Article

Multifocal Renal Cell Carcinomas With Somatic IDH2 Mutation: Report of a Previously Undescribed Neoplasm.

The American journal of surgical pathology - 1 Jan 2021

Merino Maria J, Ricketts Christopher J, Moreno Vanessa, Yang Ye, Fan Teresa W M, Lane Andrew N, Meltzer Paul S, Vocke Cathy D, Crooks Daniel R, Linehan William M

Abstract excerpt

Renal cell carcinoma (RCC) is a heterogenous disease composed of several different cancer types characterized by distinct histologies and genetic alterations, including mutation of the Krebs cycle enzyme genes for fumarate hydratase and succinate dehydrogenase (SDH). This report describes a patient with multifocal renal tumors that presented with a novel, biphasic histologic morphology with one component...

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Identifiers

PMID: 33165095
DOI: 10.1097/PAS.0000000000001611
PMCID: PMC7736215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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