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Clinicopathological and molecular features of so-called low-grade oncocytic fumarate hydratase–deficient renal cell carcinoma: a study of 5 cases

30 Apr 2025

Abstract excerpt

Low-grade oncocytic fumarate hydratase-deficient renal cell carcinoma (FHdRCC), resembling succinate dehydrogenase-deficient RCC morphologically, is a recently described uncommon variant of FHdRCC. We report five additional cases to enhance the understanding of this rare tumor type. These tumors had variably thick fibromuscular capsules with frequent intracapsular invasions and had prominently compact nests...

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PMID: 40304778
DOI: 10.1007/s00428-025-04111-8

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