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DNA damage and mitochondria in cancer and aging

28 Oct 2020

Abstract excerpt

Age and DNA repair deficiencies are strong risk factors for developing cancer. This is reflected in the comorbidity of cancer with premature aging diseases associated with DNA damage repair deficiencies. Recent research has suggested that DNA damage accumulation, telomere dysfunction and the accompanying mitochondrial dysfunction exacerbate the aging process and may increase the risk of cancer development. Thus,...

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PMID: 33146705
DOI: 10.1093/carcin/bgaa114

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