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Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells

16 Oct 2009

Abstract excerpt

BACKGROUND: Aberrant activity of tyrosine-phosphorylated proteins is commonly associated with HCC metastasis. Cell signaling events driven by these proteins are implicated in numerous processes that alter cancer cell behavior. Exploring the activities and signaling pathways of these proteins in HCC metastasis may help in identifying new candidate molecules for HCC-targeted therapy. METHODS: Hep3B (a nonmetastatic...

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Share to HER2/EGFR in Cancer Research
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PMID: 19835603
DOI: 10.1186/1471-2407-9-366

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