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Article

Pervasive RNA Secondary Structure in the Genomes of SARS-CoV-2 and Other Coronaviruses

2 Nov 2020

Abstract excerpt

The detection and characterization of large-scale RNA secondary structure in the genome of SARS-CoV-2 indicate an extraordinary and unsuspected degree of genome structural organization; this could be effectively visualized through a newly developed contour plotting method that displays positions, structural features, and conservation of RNA secondary structure between related viruses. Such RNA structure imposes a...

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PMID: 33127861
DOI: 10.1128/mbio.01661-20

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