Article
Intercalated Treatment Following Rebiopsy Is Associated with a Shorter Progression-Free Survival of Osimertinib Treatment.
Cancer research and treatment - 1 Oct 2018
Tseng Jeng-Sen, Yang Tsung-Ying, Chen Kun-Chieh, Hsu Kuo-Hsuan, Huang Yen-Hsiang, Su Kang-Yi, Yu Sung-Liang, Chang Gee-Chen
Abstract excerpt
PURPOSE: Epidermal growth factor receptor (EGFR) T790M mutation serves as an important predictor of osimertinib efficacy. However, little is known about how it works among patients with various timings of T790M emergence and treatment. MATERIALS AND METHODS: Advanced EGFR-mutant lung adenocarcinoma patients with positive T790M mutation in tumor were retrospectively enrolled and observed to determine the outcomes...
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