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Article

ERCC3, a new ovarian cancer susceptibility gene?

European journal of cancer (Oxford, England : 1990) - 1 Dec 2020

Stradella Agostina, Del Valle Jesús, Rofes Paula, Vargas-Parra Gardenia, Salinas Mónica, González Sara, Montes Eva, López-Doriga Adriana, Gómez Carolina, de Cid Rafael, Darder Esther, Teulé Alex, Solanes Ares, Munté Elisabet, Capellà Gabriel, Pineda Marta, Feliubadaló Lidia, Brunet Joan, Lázaro Conxi

Abstract excerpt

BACKGROUND: Hereditary breast and ovarian cancer syndrome (HBOC) is an inherited disorder with an increased risk of breast cancer (BC) and ovarian cancers (OC). Mutations in BRCA1-BRCA2 explains less than a half of cases. In the last decade several genes with different penetrance have been associated with an increased risk of BC or OC. A recurrent heterozygous ERCC3 truncating mutation increases the risk for...

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PMID: 33125943
DOI: 10.1016/j.ejca.2020.09.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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