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Article

Targeted next-generation sequencing of 21 candidate genes in hereditary ovarian cancer patients from the Republic of Bashkortostan.

Journal of ovarian research - 4 Apr 2023

Prokofyeva D S, Mingazheva E T, Valova Ya V, Sakaeva D D, Faishanova R R, Nurgalieva A Kh, Valiev R R, Bogdanova N, Dörk T, Khusnutdinova E K

Abstract excerpt

About 5-10% of all ovarian cancer cases show familial clustering, and some 15-25% of familial ovarian cancer cases are mediated by high-penetrance mutations in the BRCA1 and BRCA2 genes. Only few other genes have been identified for familial ovarian cancer.We conducted targeted next-generation sequencing of the protein coding region of 21 candidate genes, including UTR regions, in genomic DNA samples of 48...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 37013556
DOI: 10.1186/s13048-023-01119-z
PMCID: PMC10071671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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