Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Engineering a vector-based pan-Leishmania vaccine for humans: proof of principle

29 Oct 2020

Abstract excerpt

Leishmaniasis is a spectrum of diseases transmitted by sand fly vectors that deposit Leishmania spp. parasites in the host skin during blood feeding. Currently, available treatment options are limited, associated with high toxicity and emerging resistance. Even though a vaccine for human leishmaniasis is considered an achievable goal, to date we still do not have one available, a consequence (amongst other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 33122717
DOI: 10.1038/s41598-020-75410-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Engineering a vector-based pan-Leishmania vaccine for humans: proof of principlePMID 33122717Read ↗

<i>Leishmania</i>vaccines: progress and problemsSemantic proximity Read ↗

Preclinical validation of a second generation leishmanization vaccine against vector transmitted fatal visceral leishmaniasisSemantic proximity Read ↗

Unraveling the Immune Response Dynamics of Leishmaniasis: Insights, Challenges, and Vaccine DevelopmentSemantic proximity Read ↗

<i>Phlebotomus papatasi</i> sand fly salivary protein diversity and immune response potential in Egypt and Jordan populationsSemantic proximity Read ↗

A Second Generation Leishmanization Vaccine with a Markerless Attenuated <i>Leishmania major</i> Strain using CRISPR gene editingSemantic proximity Read ↗

Intradermal Synthetic DNA Vaccination Generates Leishmania -Specific T Cells in the Skin and Protection against Leishmania majorSemantic proximity Read ↗

The potential impact of human visceral leishmaniasis vaccines on population incidenceSemantic proximity Read ↗

Designing of a new multi-epitope vaccine against Leishmania major using Leish-F1 epitopes: An In-silico studySemantic proximity Read ↗

Leishmaniasis: Current Status of Vaccine DevelopmentSemantic proximity Read ↗

Safety, effectiveness, and skin immune response in a controlled human infection model of sand fly transmitted cutaneous leishmaniasisSemantic proximity Read ↗

<i>Leishmania</i>, microbiota and sand fly immunitySemantic proximity Read ↗

MVA-LACK as a safe and efficient vector for vaccination against leishmaniasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.