Article
Comparable human reconstitution following Cesium-137 versus X-ray irradiation preconditioning in immunodeficient NOG mice.
PloS one - 1 Jan 2020
Andersen Anna Halling Folkmar, Nielsen Stine Sofie Frank, Olesen Rikke, Harslund Jakob Le Fèvre, Søgaard Ole Schmeltz, Østergaard Lars, Denton Paul W, Tolstrup Martin
Abstract excerpt
Humanized mouse models are used extensively in research involving human pathogens and diseases. However, most of these models require preconditioning. Radio-active sources have been used routinely for this purpose but safety issues have motivated researchers to transition to chemical or X-ray based preconditioning. In this study, we directly compare 350 kV X-ray and Cs-137 low-dose precondition of NOG mice before...
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