Article
Dynamic analysis of circulating tumor DNA to predict prognosis and monitor therapeutic response in metastatic relapsed cervical cancer.
International journal of cancer - 15 Feb 2021
Tian Xiaoyuan, Ge Dongcen, Zhang Feng, Zhang Bocheng, Bai Wanting, Xu Xiaoying, Li Zongjuan, Cao Ying, Li Peiying, Zou Kun, Zou Lijuan
Abstract excerpt
Limited and inefficient treatment options exist for metastatic relapsed cervical cancer (MRCC), and there are currently no reliable indicators to guide therapeutic selection. We performed deep sequencing analyses targeting 322 cancer-related genes in plasma cell-free DNA and matched white blood cells in 173 serial blood samples from 82 locally advanced CC (LACC) or MRCC patients and when possible during...
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