Article
Spectrum of genes for inherited hearing loss in the Israeli Jewish population, including the novel human deafness gene ATOH1.
Clinical genetics - 1 Oct 2020
Brownstein Zippora, Gulsuner Suleyman, Walsh Tom, Martins Fábio T A, Taiber Shahar, Isakov Ofer, Lee Ming K, Bordeynik-Cohen Mor, Birkan Maria, Chang Weise, Casadei Silvia, Danial-Farran Nada, Abu-Rayyan Amal, Carlson Ryan, Kamal Lara, Arnthórsson Asgeir Ö, Sokolov Meirav, Gilony Dror, Lipschitz Noga, Frydman Moshe, Davidov Bella, Macarov Michal, Sagi Michal, Vinkler Chana, Poran Hana, Sharony Reuven, Samra Nadra, Zvi Na'ama, Baris-Feldman Hagit, Singer Amihood, Handzel Ophir, Hertzano Ronna, Ali-Naffaa Doaa, Ruhrman-Shahar Noa, Madgar Ory, Sofrin-Drucker Efrat, Peleg Amir, Khayat Morad, Shohat Mordechai, Basel-Salmon Lina, Pras Elon, Lev Dorit, Wolf Michael, Steingrimsson Eirikur, Shomron Noam, Kelley Matthew W, Kanaan Moien N, Allon-Shalev Stavit, King Mary-Claire, Avraham Karen B
Abstract excerpt
Mutations in more than 150 genes are responsible for inherited hearing loss, with thousands of different, severe causal alleles that vary among populations. The Israeli Jewish population includes communities of diverse geographic origins, revealing a wide range of deafness-associated variants and enabling clinical characterization of the associated phenotypes. Our goal was to identify the genetic causes of...
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