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Article

Genetic Landscape of Hearing Loss in Brazilian Patients Reveals Population-Specific Variants and Clinical Correlations.

Clinical genetics - 1 Aug 2026

Diogo-Cavassana Stella, Alencar-Coutinho Danillo, Abreu-Oberhuber Rafaella, Paramo-Neto Maria Eduarda, Oiticica Jeanne, Bento Ricardo Ferreira, Batissoco Ana Carla, Lezirovitz Karina

Abstract excerpt

Hearing loss (HL) is the most prevalent sensory disorder globally and a major public health challenge in Brazil, affecting over 1.5 million individuals. While over 150 HL-associated genes have been identified, the genetic architecture in underrepresented populations remains poorly defined, often limiting diagnostic yield and precision medicine. We assessed the diagnostic performance of a comprehensive 218-gene HL...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42233699
DOI: 10.1111/cge.70186
PMCID: PMC13327172

Genes

BSND
GJB2
GJB6
MYO15A
MYO7A
PEX6
USH1C
WFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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