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Article

E3 Ubiquitin ligase NEDD4 family‑regulatory network in cardiovascular disease

1 Jan 2020

Abstract excerpt

Protein ubiquitination represents a critical modification occurring after translation. E3 ligase catalyzes the covalent binding of ubiquitin to the protein substrate, which could be degraded. Ubiquitination as an important protein post-translational modification is closely related to cardiovascular disease. The NEDD4 family, belonging to HECT class of E3 ubiquitin ligases can recognize different substrate...

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PMID: 33110392
DOI: 10.7150/ijbs.48437

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