Article
Prevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease.
Gastroenterology - 1 Feb 2021
Naito Takeo, Botwin Gregory J, Haritunians Talin, Li Dalin, Yang Shaohong, Khrom Michelle, Braun Jonathan, Abbou Lisa, Mengesha Emebet, Stevens Christine, Masamune Atsushi, Daly Mark, McGovern Dermot P B
Abstract excerpt
BACKGROUND AND AIMS: The largest cause of mortality in patients with inflammatory bowel disease (IBD) remains thromboembolic disease (TED). Recent reports have demonstrated that both monogenic and polygenic factors contribute to TED and 10% of healthy subjects are genetically at high risk for TED. Our aim was to utilize whole-exome sequencing and genome-wide genotyping to determine the proportion of IBD patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.