Article
Genetic predisposition to thrombophilia in inflammatory bowel disease.
Journal of clinical gastroenterology - 1 Mar 2011
Cappello Maria, Grimaudo Stefania, Bravatá Ivana, Randazzo Claudia, Pipitone Rosaria Maria, Licata Anna, Cammá Calogero, Craxì Antonio
Abstract excerpt
BACKGROUND: Inflammatory bowel disease (IBD) is linked to a definite risk of thromboembolic events (TE), but data on the role of prothrombotic genetic mutations are conflicting. STUDY: Fourteen genetic factors involved in TE pathogenesis were investigated in a homogeneous cohort of Sicilian patients with IBD with and without history of TE and in healthy controls. Forty IBD patients (21 CD, 19 UC) and 20 healthy...
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