Article
Genetic markers and phosphoprotein forms of beta-catenin pβ-Cat552 and pβ-Cat675 are prognostic biomarkers of cervical cancer.
EBioMedicine - 1 Nov 2020
Scholl Suzy M, Beal Jonas, de Koning Leanne, Girard Elodie, Popovic Marina, de la Rochefordière Anne, Lecuru Fabrice, Fourchotte Virginie, Ngo Charlotte, Floquet Anne, Berns Els Mjj, Kenter Gemma, Gestraud Pierre, von der Leyen Heiko, Lecerf Charlotte, Puard Vincent, Roman Sergio Roman, Latouche Aurelien, Kereszt Attila, Balint Balazs, Rouzier Roman, Kamal Maud
Abstract excerpt
BACKGROUND: Cervical cancer (CC) remains a leading cause of gynaecological cancer-related mortality world wide and constitutes the third most common malignancy in women. The RAIDs consortium (http://www.raids-fp7.eu/) conducted a prospective European study [BioRAIDs (NCT02428842)] with the objective to stratify CC patients for innovative treatments. A "metagene" of genomic markers in the PI3K pathway and...
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