Article
CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption.
Scientific reports - 22 Oct 2020
Chen I-Chun, Kuo Po-Hsiu, Yang Albert C, Tsai Shih-Jen, Liu Tung-Hsia, Liu Hung-Jen, Lan Tsuo-Hung, Chen Hong-Ming, Huang Huang-Nan, Chung Ren-Hua, Liu Yu-Li
Abstract excerpt
Molecular mechanisms that prompt or mitigate excessive alcohol consumption could be partly explained by metabolic shifts. This genome-wide association study aims to identify the susceptibility gene loci for excessive alcohol consumption by jointly measuring weekly alcohol consumption and γ-GT levels. We analysed the Taiwan Biobank data of 18,363 Taiwanese people, including 1945 with excessive alcohol use. We...
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